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Jessica Hennessey, MD, PhD

Jessica A. Hennessey, MD, PhD is the Esther Aboodi Assistant Professor of Medicine at Columbia University Irving Medical Center and Director of Electrophysiology for NewYork-Presbyterian Westchester. She is a board-certified cardiologist and clinical cardiac electrophysiologist with expertise in the diagnosis and treatment of atrial fibrillation, ventricular arrhythmias, inherited arrhythmia syndromes, and complex rhythm disorders associated with congenital and genetic heart disease. In addition to caring for patients at Columbia University Irving Medical Center, she provides specialized electrophysiology care throughout the NewYork-Presbyterian Westchester network, helping to expand access to advanced arrhythmia management across the region.

Dr. Hennessey earned both her MD and PhD from Duke University School of Medicine. She completed her internship and residency in Internal Medicine at Massachusetts General Hospital, where she developed a strong foundation in academic medicine and cardiovascular disease. She subsequently completed fellowships in Cardiovascular Disease and Clinical Cardiac Electrophysiology at Columbia University Irving Medical Center, where she joined the faculty upon completion of her training. She is board certified in Internal Medicine, Cardiovascular Disease, and Clinical Cardiac Electrophysiology.

Her clinical practice focuses on the comprehensive management of cardiac arrhythmias using the latest advances in catheter ablation, implantable cardiac rhythm devices, left atrial appendage occlusion, and medical therapy. She has particular expertise in atrial fibrillation, ventricular tachycardia, inherited arrhythmia syndromes, and the care of patients with congenital and structural heart disease. Dr. Hennessey has a special interest in integrating genetic information into the diagnosis and treatment of cardiovascular disease, allowing for individualized management strategies for patients and their families with inherited cardiac conditions.

As Director of Electrophysiology for NewYork-Presbyterian Westchester, Dr. Hennessey has worked to expand regional access to advanced electrophysiology services while fostering collaboration between community practices and a leading academic medical center. She is committed to delivering evidence-based, patient-centered care and to incorporating emerging technologies—including pulsed field ablation, physiologic pacing, advanced electroanatomic mapping, and contemporary cardiac implantable electronic device therapies—into clinical practice when supported by the best available evidence.

Dr. Hennessey is actively involved in clinical research and education. Her academic interests include atrial fibrillation, inherited arrhythmia syndromes, sports cardiology, cardiac implantable electronic devices, and innovations in catheter ablation technology. She has participated in multicenter clinical investigations evaluating novel mapping technologies and pulsed field ablation and regularly teaches fellows, residents, and medical students in the field of cardiac electrophysiology.

Known for her thoughtful and collaborative approach to patient care, Dr. Hennessey is dedicated to helping patients understand their heart rhythm disorders and make informed treatment decisions. She combines advanced procedural expertise with compassionate longitudinal care, striving to improve quality of life and long-term cardiovascular outcomes for patients with both common and highly complex cardiac arrhythmias.

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